Immunohistochemical identification of tumours of adipocytic differentiation using an antibody to aP2 protein.
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aP2 Protein Expression as a Diagnostic Marker in Soft Tissue Tumours
PURPOSE/METHODS The aP2 gene product (aP2 protein) is known to be expressed by preadipocytes and other immature fat cells in vitro. A mouse monoclonal antibody raised against an 18 amino acid segment of the aP2 protein was found to react with lipoblasts and fetal fat cells in paraffin sections of soft tissue tumours of adipose differentiation. In this immunohistochemical study, we have further ...
متن کاملAn Immunohistochemical Study Of P63 Protein Expression In Meningioma
Background and Objective: Histological grading has prognostic and therapeutic implications in meningioma. However, histological criteria are sometimes not fulfilled to predict the biological behavior of meningiomas. P63 gene is a novel P53 family member, known as tumor suppressor factor, with multiple isoforms and shows high expression in many normal and neoplastic human tissues. In this stu...
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ژورنال
عنوان ژورنال: Journal of Clinical Pathology
سال: 1995
ISSN: 0021-9746
DOI: 10.1136/jcp.48.10.950